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Headache, particularly at initiation Mild anxiety or restlessness with some compounds Nasal irritation (intranasal administration) Sleep disturbance if dosed too close to bedtime Rare: Mood changes or emotional lability Dihexa (PNB-0408, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a potent hepatocyte growth factor (HGF) receptor agonist originally developed at Washington State University

KPV appears safe but may cause mild injectionsite irritation or gastrointestinal upset

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Low vitamin D levels have been linked to increased risk of heart diseases such as hypertension, heart failure, and stroke